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    最近搜索:細(xì)胞培養(yǎng) 微生物學(xué) 分子生物 生物化學(xué)
    首頁(yè)>>免疫學(xué)>>一抗>>Fas相關(guān)1因子抗體
    Fas相關(guān)1因子抗體
    • 產(chǎn)品貨號(hào):
      BN41694R
    • 中文名稱:
      Fas相關(guān)1因子抗體
    • 英文名稱:
      Rabbit anti-FAF1 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號(hào)

      產(chǎn)品規(guī)格

      售價(jià)

      備注

    • BN41694R-50ul

      50ul

      ¥1486.00

      交叉反應(yīng):Human,Rat(predicted:Mouse,Chicken,Dog,Cow,Rabbit) 推薦應(yīng)用:IHC-P,IHC-F,IF,ELISA

    • BN41694R-100ul

      100ul

      ¥2360.00

      交叉反應(yīng):Human,Rat(predicted:Mouse,Chicken,Dog,Cow,Rabbit) 推薦應(yīng)用:IHC-P,IHC-F,IF,ELISA

    • BN41694R-200ul

      200ul

      ¥3490.00

      交叉反應(yīng):Human,Rat(predicted:Mouse,Chicken,Dog,Cow,Rabbit) 推薦應(yīng)用:IHC-P,IHC-F,IF,ELISA

    產(chǎn)品描述

    英文名稱FAF1
    中文名稱Fas相關(guān)1因子抗體
    別    名Fas associated factor 1; CGI; FAF1 protein; Fas (TNFRSF6) associated factor 1; FAS associated factor 1; FLJ37524; hFAF1; HFAF1s; Protein FAF1; CGI 03; FAF1; FAF1_HUMAN; Fas associated protein factor 1; FAS-associated factor 1; UBX domain protein 3A; UBX domain-containing protein 12; UBX domain-containing protein 3A; UBXD12; UBXN3A; TNFRSF6 associated factor 1.  



    研究領(lǐng)域細(xì)胞生物  免疫學(xué)  
    抗體來(lái)源Rabbit
    克隆類型Polyclonal
    交叉反應(yīng)Human, Rat,  (predicted: Mouse, Chicken, Dog, Cow, Rabbit, )
    產(chǎn)品應(yīng)用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/test IF=1:100-500 (石蠟切片需做抗原修復(fù))
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量74kDa
    細(xì)胞定位細(xì)胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human FAF1:551-650/650 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹FAF1 (Fas-associated protein factor 1) specifically interacts with the cytoplasmic domain of wild type, but not mutated, Fas in both yeast and mammalian cells. It is transiently expressed in T cells and potentiates Fas-induced apoptosis. FAF1 lacks a DDH (Death domain homologous region), in contrast to TRADD, FADD, and RIP, and cannot induce apoptosis independent of Fas activation. Fas associated factor 1; CGI ; FAF1 protein; Fas (TNFRSF6) associated factor 1; FAS associated factor 1; FLJ37524; hFAF1; HFAF1s; Protein FAF1; TNFRSF6 associated factor 1.

    Function:
    Potentiates but cannot initiate FAS-induced apoptosis.

    Subunit:
    Specifically interacts with the cytoplasmic domain of FAS. Interacts with NLRP12 DAPIN/PYRIN domain via its UBA domain.

    Subcellular Location:
    Nucleus.

    Tissue Specificity:
    Most abundant in testis, slightly less abundant in skeletal muscle and heart, followed by prostate, thymus, ovary, small intestine, and colon. Not detected in the peripheral blood leukocytes.

    Similarity:
    Contains 1 UBA domain.
    Contains 1 UBX domain.

    SWISS:
    Q9UNN5

    Gene ID:
    11124

    Database links:

    Entrez Gene: 11124 Human

    Entrez Gene: 14084 Mouse

    Entrez Gene: 140657 Rat

    Omim: 604460 Human

    SwissProt: Q9UNN5 Human

    SwissProt: P54731 Mouse

    SwissProt: Q924K2 Rat

    Unigene: 530402 Human

    Unigene: 318259 Mouse

    Unigene: 198288 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.