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產品規(guī)格
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BN41527R-50ul
50ul
￥1486.00
交叉反應：Rat,Mouse,Human 推薦應用：IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41527R-100ul
100ul
￥2360.00
交叉反應：Rat,Mouse,Human 推薦應用：IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41527R-200ul
200ul
￥3490.00
交叉反應：Rat,Mouse,Human 推薦應用：IHC-P,IHC-F,IF,Flow-Cyt,ELISA
產品描述
| 英文名稱 | AEBP1 |
| 中文名稱 | 脂肪細胞增強結合蛋白1 |
| 別 名 | AE binding protein 1; ACLP; Adipocyte enhancer binding protein 1; AEBP 1; AEBP1; Aortic carboxypeptidase like protein ACLP;Aortic carboxypeptidase like protein; FLJ33612; AEBP1_HUMAN; Adipocyte enhancer-binding protein 1; AE-binding protein 1; Aortic carboxypeptidase-like protein. |
| 研究領域 | 免疫學 染色質和核信號 轉錄調節(jié)因子 結合蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Human, (predicted: Mouse, Rat, ) |
| 產品應用 | ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/test IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 128/80kDa |
| 細胞定位 | 細胞核 細胞漿 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human AEBP1:101-200/728 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產品介紹 | This gene encodes a member of carboxypeptidase A protein family. The encoded protein may function as a transcriptional repressor and play a role in adipogenesis and smooth muscle cell differentiation. Studies in mice suggest that this gene functions in wound healing and abdominal wall development. Overexpression of this gene is associated with glioblastoma. [provided by RefSeq, May 2013]. Function: May positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation. May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness. Can act as a transcriptional repressor. Subunit: Interacts with GNG5, NFKBIA, MAPK1, MAPK3 and PTEN. May interact with calmodulin. Binds to DNA in vitro. Subcellular Location: Isoform 1: Secreted. Isoform 2: Cytoplasm (Probable). Nucleus (Probable). Tissue Specificity: Expressed in osteoblast and visceral fat. Post-translational modifications: Phosphorylated by MAPK1 in vitro. Similarity: Belongs to the peptidase M14 family. Contains 1 F5/8 type C domain. SWISS: Q14113 Gene ID: 165 Database links: Entrez Gene: 165 Human Omim: 602981 Human SwissProt: Q14113 Human Unigene: 439463 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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