<strike id="amuic"></strike>
  • <abbr id="amuic"><option id="amuic"></option></abbr>
    <strike id="amuic"></strike>
    

  • <cite id="amuic"><source id="amuic"></source></cite>

    <cite id="amuic"><source id="amuic"></source></cite>
    • <ul id="amuic"><table id="amuic"></table></ul>
    


    
    
    
        
        
    
    
    

    

    
    
    
    
    
        
        
    
    
        
    

    

    
    
    
    
    
        
        
    
    
    
    最近搜索：細(xì)胞培養(yǎng) 微生物學(xué) 分子生物 生物化學(xué) 
    

    

    
	
    首頁(yè)>>免疫學(xué)>>一抗>>巢蛋白/神經(jīng)上皮干細(xì)胞蛋白抗體  
    

    

    
	
    
    	
    
        	
    巢蛋白/神經(jīng)上皮干細(xì)胞蛋白抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
    • 
                        	
      產(chǎn)品貨號(hào)：
      
                            
      BN41309R
      
                        
      • 
                    	
    • 
                        	
      中文名稱：
      
                            
      巢蛋白/神經(jīng)上皮干細(xì)胞蛋白抗體 
      
                        
      • 
                                            	
    • 
                        	
      英文名稱：
      
                            
      Rabbit anti-Nestin Polyclonal antibody 
      
                        
      • 
                                                                    	
    • 
                        	
      品牌：
      
                            
      Biorigin 
      
                        
      • 
                    
    
                
    
            
    
            
    
                    
    
                        
      
                            
    • 
                                
      貨號(hào)
      
                                
      產(chǎn)品規(guī)格
      
                                
      售價(jià)
      
                                
      備注
      
                            
      • 
                                                        
    • 
                                
      BN41309R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應(yīng)：Human(predicted:Cow)   推薦應(yīng)用：IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
      
                            
      • 
                                                        
    • 
                                
      BN41309R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應(yīng)：Human(predicted:Cow)   推薦應(yīng)用：IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
      
                            
      • 
                                                    
    
                    
    
              
    
            
    
            	
    
                	
    產(chǎn)品描述
    
                
    
                
    
                	
    英文名稱Nestin
    中文名稱巢蛋白/神經(jīng)上皮干細(xì)胞蛋白抗體
    別    名ESTM 46; FLJ 21841; FLJ21841; Intermediate filament protein; Nbla00170; Nes; NEST_RAT; Nestin.  
    研究領(lǐng)域細(xì)胞生物  發(fā)育生物學(xué)  神經(jīng)生物學(xué)  干細(xì)胞  細(xì)胞類型標(biāo)志物  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應(yīng)Human,  (predicted: Cow, )
    產(chǎn)品應(yīng)用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test ICC=1:100 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量177kDa
    細(xì)胞定位細(xì)胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human Nestin:21-120/1621 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹Nestin is a Class VI intermediate filament expressed in the developing central nervous system (CNS) in early embryonic neuroepithelial stem cells. This protein has been widely used as a predominant marker for stem / progenitor cells, glioma cells, and tumor endothelial cells in the mammalian CNS. Furthermore, it is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumor.

    Function:
    Required for brain and eye development (By similarity). Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.

    Subunit:
    Forms homodimers and homotetramers in vitro. In mixtures with other intermediate filament proteins such as vimentin and alpha-internexin, this protein preferentially forms heterodimers which can assemble to form intermediate filaments if nestin does not exceed 25%. Interacts with FHOD3.

    Subcellular Location:
    Forms homodimers and homotetramers in vitro. In mixtures with other intermediate filament proteins such as vimentin and alpha-internexin, tis protein preferentially forms heterodimers which can assemble to form intermediate filaments if nestin does not exceed 25%. Interacts with FHOD3

    Tissue Specificity:
    CNS stem cells.

    Post-translational modifications:
    Constitutively phosphorylated. This increases during mitosis when the cytoplasmic intermediate filament network is reorganized.

    Similarity:
    Belongs to the intermediate filament family.

    SWISS:
    P48681

    Gene ID:
    10763

    Database links:

    Entrez Gene: 10763 Human
    Entrez Gene: 18008 Mouse
    Entrez Gene: 25491 Rat
    Omim: 600915 Human
    SwissProt: P48681 Human
    SwissProt: Q6P5H2 Mouse
    SwissProt: P21263 Rat
    Unigene: 527971 Human
    Unigene: 331129 Mouse
    Unigene: 9701 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


    神經(jīng)干細(xì)胞標(biāo)志物
    在動(dòng)物體早期發(fā)育過程中，中樞神經(jīng)系統(tǒng)發(fā)育尤為重要 。Nestin是一種中等纖維蛋白，它在哺乳動(dòng)物神經(jīng)前體細(xì)胞中表達(dá)較高，目前已被廣泛用于神經(jīng)前體細(xì)胞的重要標(biāo)志分子。研究Nestin的表達(dá)調(diào)控規(guī)律，將有助于人們認(rèn)識(shí)神經(jīng)前體細(xì)胞的生物特性。此抗體還表達(dá)中樞神經(jīng)系統(tǒng)干細(xì)胞及神經(jīng)上皮細(xì)胞。