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    首頁(yè)>>免疫學(xué)>>一抗>>垂體瘤細(xì)胞凋亡抗體  
    

    

    
	
    
    	
    
        	
    垂體瘤細(xì)胞凋亡抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產(chǎn)品貨號(hào)：
      
                            
      BN41257R
      
                        
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      中文名稱：
      
                            
      垂體瘤細(xì)胞凋亡抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-RHBDD3 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號(hào)
      
                                
      產(chǎn)品規(guī)格
      
                                
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      備注
      
                            
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      BN41257R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應(yīng)：Human,Mouse(predicted:Rat)   推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA
      
                            
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      BN41257R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應(yīng)：Human,Mouse(predicted:Rat)   推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA
      
                            
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    產(chǎn)品描述
    
                
    
                
    
                	
    英文名稱RHBDD3
    中文名稱垂體瘤細(xì)胞凋亡抗體
    別    名C22orf3; HS984G1A; Pituitary tumor apoptosis; PTAG; RHBD3_HUMAN; RHBDD3; Rhomboid domain containing 3; Rhomboid domain-containing protein 3.  
    研究領(lǐng)域細(xì)胞生物  神經(jīng)生物學(xué)  細(xì)胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  
    抗體來(lái)源Rabbit
    克隆類型Polyclonal
    交叉反應(yīng)Human, Mouse,  (predicted: Rat, )
    產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量40kDa
    細(xì)胞定位細(xì)胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human RHBDD3:151-250/386 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹PTAG is a novel 386 amino acid multi-pass membrane protein that contains one UBA domain and augments drug-induced apoptosis. Cells lacking PTAG have a reduced apoptotic response, thereby causing a predisposition to cell malignancy and resistance to chemotherapeutic interventions, and PTAG plays a role in colorectal tumorigenesis as the majority of primary colorectal tumors lack the PTAG gene. Encoded by a gene located on human chromosome 22, PTAG is often co-expressed with EWS (ewing sarcoma breakpoint region 1), a gene located directly downstream of PTAG.

    Subcellular Location:
    Membrane; Multi-pass membrane protein (Potential).

    Similarity:
    Contains 1 UBA domain

    SWISS:
    Q9Y3P4

    Gene ID:
    25807

    Database links:
    Entrez Gene: 25807 Human
    Entrez Gene: 279766 Mouse
    Entrez Gene: 289753 Rat
    SwissProt: Q9Y3P4 Human
    SwissProt: Q8BP97 Mouse
    SwissProt: Q642B3 Rat
    Unigene: 106730 Human
    Unigene: 260866 Mouse
    Unigene: 9606 Rat


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    RHBDD3分子是一個(gè)全新的TLR信號(hào)途徑的負(fù)向調(diào)控蛋白分子,是一個(gè)能夠顯著抑制自身免疫性疾病發(fā)生的效應(yīng)分子,RHBDD3控制機(jī)體避免發(fā)生過(guò)度的免疫應(yīng)答、防止自身免疫性疾病的發(fā)生具有重要意義。












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