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    首頁>>免疫學(xué)>>一抗>>Ras-GTP酶激活蛋白3抗體  
    

    

    
	
    
    	
    
        	
    Ras-GTP酶激活蛋白3抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產(chǎn)品貨號(hào)：
      
                            
      BN41181R
      
                        
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      中文名稱：
      
                            
      Ras-GTP酶激活蛋白3抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-RASA3 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號(hào)
      
                                
      產(chǎn)品規(guī)格
      
                                
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      備注
      
                            
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      BN41181R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應(yīng)：Human,Mouse(predicted:Rat,Chicken,Dog,Pig,Cow,Horse)   推薦應(yīng)用：WB,ELISA
      
                            
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      BN41181R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應(yīng)：Human,Mouse(predicted:Rat,Chicken,Dog,Pig,Cow,Horse)   推薦應(yīng)用：WB,ELISA
      
                            
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    產(chǎn)品描述
    
                
    
                
    
                	
    英文名稱RASA3
    中文名稱Ras-GTP酶激活蛋白3抗體
    別    名GAP III; GAP1(IP4BP); GAP1IP4BP; GAPIII; GTPase activating protein III; Inositol 1 3 4 5 tetrakisphosphate binding protein; Inositol 1345 tetrakisphosphate binding protein; Ins P4 binding protein; Ins(1 3 4 5)P4 binding protein; Ins(1345)P4 binding protein; Ras GTPase activating protein 3; RAS p21 protein activator 3; RASA 3.RASA3_HUMAN  
    研究領(lǐng)域免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應(yīng)Human, Mouse,  (predicted: Rat, Chicken, Dog, Pig, Cow, Horse, )
    產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量91kDa
    細(xì)胞定位細(xì)胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human RASA3:501-600/834 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹RASA3 is a inhibitory regulator of the Ras-cyclic AMP pathway and is a member of the GAP1 family of GTPase-activating proteins. It stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. RASA3 is an inositol 1,3,4,5-tetrakisphosphate-binding protein (IP4).

    Function:
    Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) with high affinity. Might be a specific IP4 receptor.

    Subcellular Location:
    Cell membrane.

    Similarity:
    Contains 1 Btk-type zinc finger.
    Contains 2 C2 domains.
    Contains 1 PH domain.
    Contains 1 Ras-GAP domain.

    SWISS:
    Q14644

    Gene ID:
    22821

    Database links:
    Entrez Gene: 22821 Human
    Entrez Gene: 19414 Mouse
    Entrez Gene: 29372 Rat
    Omim: 605182 Human
    SwissProt: Q14644 Human
    SwissProt: Q60790 Mouse
    SwissProt: Q9QYJ2 Rat
    Unigene: 593075 Human
    Unigene: 18517 Mouse
    Unigene: 224604 Rat


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.