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    最近搜索:細(xì)胞培養(yǎng) 微生物學(xué) 分子生物 生物化學(xué)
    首頁(yè)>>免疫學(xué)>>一抗>>結(jié)締組織生長(zhǎng)因子抗體
    結(jié)締組織生長(zhǎng)因子抗體
    • 產(chǎn)品貨號(hào):
      BN40687R
    • 中文名稱:
      結(jié)締組織生長(zhǎng)因子抗體
    • 英文名稱:
      Rabbit anti-CTGF Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號(hào)

      產(chǎn)品規(guī)格

      售價(jià)

      備注

    • BN40687R-100ul

      100ul

      ¥2360.00

      交叉反應(yīng):Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Rabbit) 推薦應(yīng)用:WB

    • BN40687R-200ul

      200ul

      ¥3490.00

      交叉反應(yīng):Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Rabbit) 推薦應(yīng)用:WB

    產(chǎn)品描述

    英文名稱CTGF
    中文名稱結(jié)締組織生長(zhǎng)因子抗體
    別    名CCN 2; CCN-2; CCN2; Connective Tissue Growth Factor; CTGF; Hcs 24; Hcs24; Hypertrophic chondrocyte specific protein 24; Hypertrophic chondrocyte-specific gene product 24; Insulin-like Growth Factor-Binding Protein 8; MGC102839; NOV 2; NOV2; Connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP8; IGFBP-8; connective tissue growth factor precursor; CTGF_HUMAN.  
    研究領(lǐng)域心血管  免疫學(xué)  生長(zhǎng)因子和激素  
    抗體來(lái)源Rabbit
    克隆類型Polyclonal
    交叉反應(yīng)Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Rabbit, )
    產(chǎn)品應(yīng)用WB=1:500-2000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量36kDa
    細(xì)胞定位細(xì)胞外基質(zhì) 分泌型蛋白 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human CTGF:27-120/349 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009].

    Function:
    Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.

    Subunit:
    Monomer.

    Subcellular Location:
    Secreted, extracellular space, extracellular matrix. Secreted.

    Tissue Specificity:
    Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested.

    Similarity:
    Belongs to the CCN family.
    Contains 1 CTCK (C-terminal cystine knot-like) domain.
    Contains 1 IGFBP N-terminal domain.
    Contains 1 TSP type-1 domain.
    Contains 1 VWFC domain.

    SWISS:
    P29279

    Gene ID:
    1490

    Database links:

    Entrez Gene: 1490 Human

    Entrez Gene: 64032 Rat

    Omim: 121009 Human

    SwissProt: P29279 Human

    SwissProt: P29268 Mouse

    SwissProt: Q9R1E9 Rat

    Unigene: 410037 Human

    Unigene: 390287 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    生長(zhǎng)因子和激素( Growth Factor and Hormones)
    結(jié)締組織生長(zhǎng)因子(CTGF)是調(diào)節(jié)細(xì)胞增生、分化和細(xì)胞外基質(zhì)形成的重要效應(yīng)分子,可調(diào)節(jié)機(jī)體有關(guān)組織、細(xì)胞生長(zhǎng)并與纖維化發(fā)生密切相關(guān)的一種因子,因而在肌體的各類創(chuàng)傷修復(fù)過(guò)程中具有重要的生理學(xué)意義。



















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